All About Apis Mellifica—The Stinging Homeopathic Medicine


IIMG_1329n this guest blog, American homeopath, educator of families on how to use homeopathy, and mom Joette Calabrese, HMC, CCH, RSHom(Na) shares her tips on how to use one of the most popular homeopathic single medicines, Apis mellifica. For more tips, tricks and secrets on getting and staying healthy, as well as articles, upcoming seminars and events on homeopathy, visit

Imagine having a non-drowsy medicine that will relieve the pain, swelling and even danger caused by a bee sting. What if a medicine could do all that and cost less than $20? Does it seem too good to be true? Welcome to the world of homeopathy—a world of infinite capabilities to heal, soothe and comfort the ailments of bee stings and the like.

Apis mellifica, otherwise known as Apis, is made from a honeybee. In an FDA-regulated homeopathic pharmacy, a honeybee is crushed, added to alcohol, and then diluted so many times the offending aspect of the bee venom is removed, leaving only the curative agent. After this procedure, it becomes a powerful medicine for an actual honeybee sting and for ailments that have similar symptoms.

Swelling, watery-filled localized areas of redness and inflammation are the hallmark of Apis. The affected area has a puffy appearance and sometimes looks like bags of water under the skin. This is not unlike the edema produced by allergic reactions. More often than not, it occurs under the eyes and is sometimes accompanied by hives. When an eye is nearly shut with swelling, Apis is probably the correct medicine. Hence, the most common conditions Apiswill relieve are eye infections such as conjunctivitis and styes, sore throats, hives, stings from insects, and urinary tract infections.

LApis_mellificaet me offer an example. My aunt, who had been prone to styes in her twenties, was suddenly revisited in her 70s by this painful and cumbersome malady. Her doctor gave her an antibiotic that brought down the swelling and pain in short order. This was the method used for the first, second and third ones, but by the fourth outbreak, only months later, she called me. As usual, her eye was quite swollen and red, but she reported that each outbreak was becoming increasingly more painful. She described the pain as stinging and that was all that was needed for me to choose Apis30C. She took this honey of a remedy and reported a few days later the intensity of the pain diminished enough to allow her to read by the following morning. Two days later, there was still some puffiness and sensitivity, but the worst was past. This occurred over a decade ago, and there has been no return of her problem.

When pain is eased by cold applications to the troubled area and when warmth causes increased distress, it’s also most likely a call for Apis. When a sore throat is the problem, other good clues are a desire for a cold drink and aversion to or pain from a warm drink. The Apis sufferer cannot tolerate warmth from the sun or a warm room. When you observe a swollen uvula or tonsils, Apis should be considered. Despite the water-filled appearance of Apis, the sufferer is not thirsty. This contradiction is useful when a differential between two homeopathic remedies is perplexing. Sensitive skin where hives have erupted also indicates the need for Apis. The physical symptoms are sometimes accompanied byweepy sadness and irritability. A fright, “stinging” jealousy, anger or disappointment often cause a need for Apis on both a physical and emotional level.

So the next time you experience a stinging swelling with heat on the skin, in the throat, in the urinary tract or in the eye, think homeopathy and think Apis, the honeybee. You may find yourself buzzing with enthusiasm.

Comments (73)


Hello thank you for your nice post. My husband was recommended by one homeopath to use Apis Mellifica among other homeopathic remedies for sinusitis, some kind of allergy in this sinuses area.. Would you normally recomend it for sinusitis? Thank you. Ana


As a company, we indicate Apis mellifica for swelling from insect bites or allergies.


where from I could get apis mellifica in j&k


A CK is the same as a K dilution. CK dilutions are available on Amazon. I consulted with our pharmacist and he is not familiar with a j dilution, perhaps this is a nickname for a dilution found in another country.


is apis to be ingested or rubbed on hives or blisters?


Apis should be dissolved under the tongue and not rubbed on the irritation.


I have developed a contact allergy to polyester/plastic. Will this medicine help me to not have swelling, itching, hives when I come into contact with this material if I take it regularly?


Our medicines can not be used as a preventative. When you do come in contact with this material, Urtica urens 30C or Sulphur 30C can offer relief.

hare krishna moneysays:

Hi! I am a homeopathy remedy user for 32 years now 78 yrs. Personally in Charleston South Carolina while walking on the woods, some insect bitten me. The bite is on the right foot heel just nearer to bone. Since a traveller, medical aide given to me in Charleston. But it is not healing yet after 3 months. Homeopath in Ottawa Canada recommends Apis Mellica to nullify the effect of sting of the insect. What do you recommend to cure this condition so that I can wear my sock and shoe? I was given anti biotics by family doctor but no good so far. I rly totally on Homeopathy remedy. Would you pl help me thanks
hare krishna money ottawa canada


We recommend Apis mellifica 6C and Ledum palustre 6C for insect bites. Take 5 pellets of each 3 times a day until symptoms are relieved.


Hi, Boiron, are there homeopathic lotions-or-creams to treat allergy red dots and/or skin hives? Please reply.


Thank you for your question. While we do not have topicals that address this specific question, some of our single medicines (oral pellets) can address some of these issues. For example, Histaminum relieves symptoms of allergies, such as hay fever, hives or urticaria. Refer to our Boiron Medicine Finder on for more information.


What’s the difference between 6C and 30c on the apis?


Thank you for your question, Mindy. Most single homeopathic medicines like Apis are available in different dilutions. The letter indicates which dilution process was chosen, while the number indicates how many times that dilution process was used, and consequently, which symptoms the medicine is meant to treat. Low dilutions, such as 6C, will relieve local symptoms— symptom you can point a finger at (i.e., an insect bite or bruise). High dilutions, such as 30C, will relieve general symptoms—more than one symptom in more than one location with possible behavioral or emotional symptoms (i.e., a very high fever and chills, accompanied by agitation or sleeplessness). If a person has the right medicine, no matter what the dilution, he or she will see a lessening of symptoms. For most medicines, choosing the right dilution is merely fine tuning. It may be helpful for you to use our Boiron Medicine Finder at to decide which dilution is best.


Hi Boiron,
My son who is 11 has had swollen tonsils for quite some time now, which cause him to snore. What do you recommend?


Thank you for your question, Landie. Our pharmacist recommends that five pellets of Apis mellifica be taken before bedtime if drinking cold liquids improves his condition. If cold does not improve it, then five pellets of Belladonna 6C is recommended before bedtime. He also recommends that your son sleep on his side or belly for better comfort.


My 11 year old had swimmers ear, which turned into a middle ear infection. The doctor prescribed amoxicillin. On the last day of treatment ( the tenth day), my son developed horrible hives from head to toe. A few hours later, his body swelled. He developed pain and cannot walk a lot of the time. His hives are now gone, but the pain has lasted a week so far. The pain travels. Sometimes it’s in his right leg, the next day it’s in his left leg. A few hours later, it could be his arms, then his jaw, then his feet, and a day later, back to his legs. The past two nights, he had a high fever. The worst of it is at night. Sometimes he can’t even walk. The doctor doesn’t seem to care, because they can’t see his pain and it’s not bothering them.

What can I give him to help his pain? It might be getting better on its own, but it’s happening very slowly.

Also, if he ever comes into contact with another allergen, he may need an epi pen. Is there an alternative to that as well?

I really hope you can help me, because nobody else will.

Thank you.


Hello Ronni,

Thank you for contacting the Boiron Information Center.

As a manufacturer, we offer over-the-counter medicines with clear indications for acute conditions that can be safely relieved with self-medication. Each medicine is labeled with the most common acute condition it relieves. However, health care professionals may instruct their patients to use the medicine for other conditions not listed on the label.

Homeopathic treatments for chronic conditions are very specific to each patient. There may be a homeopathic treatment that addresses your condition, but we recommend consulting a practitioner knowledgeable in homeopathy. If you do not have a practitioner, please contact the National Center for Homeopathy at 703-506-7667or visit

Please do not hesitate to contact us with any further questions. Thank you.


Hi there! I recently have been getting bit by mosquitos and while i know im allergic the bite areas have turned into big red extremely itchy bumps. Will the apis help with this?


Apis mellifica 30C will work fine: take 5 pellets every 20 minutes and decrease with improvement. Take Histaminum 30C as well (5 pellets three times a day) to decrease the allergic reaction.

If you know there are mosquitoes around, you can take 5 pellets of ledum palustre 6C every hour or so: it doesn’t prevent the bites, but decreases the reaction. Use a repellant as well: there are very good organic ones.


HI I’m curious, if someone is allergic to bees or bee stings would it be dangerous for them to take Apis? Thanks you


Apis mellifica 6C and above is far too diluted to cause any harm, even in an allergic person. Use a 30C dilution, which tends to work faster. Apis works fast but doesn’t last long: take it frequently at first (every 15-20 minutes) and decrease the frequency with improvement.

Guillermo Maciassays: every season changes, turn to get sick my kids from cold-hot or hot-cold it look there take long time to adjust. Can be allergy or how their body modulate own temperature system or immune aystem.what can give to them in homepatic fluid form .


Our medicines are not indicated for the conditions you mentioned. You may want to consult your own health care practitioner that is skilled in homeopathy.

Ahsan Ul Haqsays:

i want to know about apis medllifca Mother tincture. How and where it can help us.
Homeopathic Medicine List page enlist all A to Z homoeopathic Remedies for complete information


For information about homeopathic medicines in your country, please visit our international site: Thanks.

Homeopathic Doctor Ahsansays:

Thank you for this information. Can you please Let me know that where I can buy Apis Mellifica 30?


Can this be used on my horse that has had an allergic reaction to biting flies? Her chest is swollen and semi hard and sore.


Karen, thank you for your question. Since the pathologies and symptoms are different between humans and animals, we would recommend that you consult a veterinarian skilled in homeopathy.

Natasha Edwardssays:

I have had urticaria for 14 days totally covered. My friend recommended apis 30c how much can I take?


Dear Natasha,
Thank you for your question. Our pharmacist recommends that you take Apis mellifica 30C frequently (every hour or even 30 minutes) because the medicine works fast, but does not last. You may also take Histaminum 30C and Urtica urens 6C. Please refer to the Boiron Homeopathic Medicine Finder for details:


I have Hashimoto auto immune disease and urticaria erupts on me every now and then. I am on anti histamines from long. Sometimes I need to take a steroid shot to control urticaria. This steroid thing happens two or three times a year. The urticaria mainly comes on my forehead head hands and feet only no where else. A friend of mine recommended Apis Millfica 30C. You think this will help eradicate this allergy for good? If I take this medicine shall I dis continue the ones I am taking? Mainly the antihistamines?

Also pls advise if this antihistamines affects your sexual life? If yes what alternative homeopathic Medicine has for it?



Thank you for your question. The Boiron Homeopathic Medicine Finder (available on our website or download it for free from the app store) offers protocols to relieve symptoms, but does not affect the auto-immune disease itself. We recommend trying the protocol found in the medicine finder (Histaminum 30C, Apis mellifica 30C, and Urtica urens 6C) for hives without discontinuing the use of antihistamines. If you experience relief of your symptoms, then try taking the homeopathic medicines without the antihistamines and evaluate the results. The goal is not to eradicate Hashimoto, but to decrease the need for antihistamines and steroid shots. Please contact the Boiron Information Center at 1-800-BOIRON1 or if you have further questions.



while researching homeopathic apis mellifica 6c for eye inflammation for my dog that has glaucoma. I read that can also be used to treat arthritis on humans. is that true and if so, which one should I use?

Thank you.


Thank you for your question. Our pharmacist recommends taking our Arnicare Arthritis, which contains Apis mellifica. If you have additional questions, please contact our Boiron Information Center at 1-800-BOIRON 1 or e-mail

S Msays:


My menstrual period got shorten after taking too much estrogen, and I’m suffering from estrogen dominance since then. My periods became irregular and short. I used to have 28 days cycles; now 23-26. My menses are reddish black and black clothings. I’m suffering PMS (tender breast, back pain, bloating). I’m very fatigue and have no desire to do anything. I became very lazy and sluggish, and any effort makes me exhausted. I have pain during intercourse. I grind my teeth a lot, and I get angry easily. I gained a lot of weight and can’t lose weight even after exercising (My weight used to be around 102-108 lb, and now it is 167 lb increase of more than 60% of my original weight). My homeopathic doctor prescribed for me Sepia; I took it for 3 months; it relieved my PMS, but while traveling I didn’t get period for almost 2 months; after that I got period for one month (bleeding for 4-5 days stopping for 2-3 days, and bleeding again all red blood; this continued for a month. Doctor stopped Sepia and prescribed Apis for me. I have been taking it for 2 months now; it relieved my PMS a little bit but my periods are still irregular and short (last one was 23 days) lots of black clots and last for 2-3 days only with reddish black blood. I got in a deep depression after taking Sepia and Apis.

Also after a car accident in 2008 I took 2 medications that the side effects are weight gain and water retention especially in my legs (with no physical problems). Doctors couldn’t figure out what is the reason of my edema/water retention. Since then I had to diet and exercise to lose weight; but after estrogen dominance I’m unable to lose weight.

What do you recommend for me to extend my cycles back to 28 days, get red blood (instead of black blood and clots), lose weight, lower my estrogen levels, increase progesterone levels (balance my hormones), and relief my PMS.

Thanks & Best Regards.


Thank you for contacting us. As a manufacturer, we cannot make self-medication recommendations based on the nature of your symptoms which require the consultation and advice of a healthcare professional per our pharmacist.



I have been experiencing burning sensation while urinating and went to the doctor for consultation. they ran urine tests and blood test to rule out any infection /kidney /STD . All the tests came out normal. However they couldn’t diagnose the cause of this issue.

Apart from the burning sensation , i dont experience anyother symptom. I am taking in a lot of fluids daily and Azo tablet to reduce the pain but there is no improvement.

Could you please help and advice what to do next?


Hi Ganesh, our pharmacist recommends you take five pellets of Cantharis 6C three times a day for a few days. If you have any more questions, please contact our Boiron Information Center at 1-800-BOIRON 1 or e-mail

Raj kumar Maddelasays:

Hi madam i am presently taking echinacea angustifolia for herpes outbreaks from 15 days and now its little good feeling and please suggest me can i take apis mellifica 30 combined are its safe?? And please suggest me how should i to take the dilution of apis mellifica 30..its very great full to me…thank you


Hello Raj, there are no drug interactions or contraindications, so Apis is safe to take with other treatments. Dosing and frequency will depend on the location can kind of herpes you have. You may want to check with our Medicine Finder app to find out which medicine is right for you and for information on dosing.


Hello , mam

I was sting by a honey bee 1 month ago . .. day after sting i started having hives … taking antihistaminics but effect last only 12 hrs and then again starts ……gets worsen on itching ….plz help .. homeopathy…


Hi Aditya, if you are still experiencing symptoms from a bee sting that happened a month ago, we recommend you consult with a health care professional. Generally, five pellets of Apis mellifica 30C three times a day is used for swollen, itchy skin. Additionally, Histaminum 30C can be used for allergy symptoms, including hives.


I am patient of idiopathic chronic urteceria from last seven years. Is apis mel 1m good for me.


Hi Chanda, homeopathic treatments for chronic conditions are very specific to each patient. There may be a homeopathic treatment that addresses your condition, but we recommend first consulting a practitioner knowledgeable in homeopathy. If you’re in the U.S., you can contact the National Center for Homeopathy at (856) 437-4752 or visit to find a practitioner in your area.

Jimmy hansensays:

Hi. I am taking lithium carbonate and i developed itching. Allegra and Apis are being used to control my discomfort. Any thoughts on this? Please


Hello Jimmy, we spoke with our pharmacist and he suggests you check with doctor or health care professional as itching is not a common side effect of lithium carbonate. Meanwhile, he recommends 5 pellets of Apis 30C every hour or more frequently if itching is intense, in addition to Urtica urens 6C three times a day or as needed. Please be aware that Allegra may help with itching but can cause drowsiness, so consider trying homeopathy first and keeping antihistamines as a second option.

Please feel free to contact our Boiron Information Center at 1-800-BOIRON 1 or e-mail if you have any more questions about these medicines or dosing.

VK Singhsays:

Can apis mellifica 30 be used to treat epididymal cyst? Please tell me how effective is this medicine for epididymal cyst?

Any recommendation for this disease?


Hello VK, according to our pharmacist, Apis mellifica is used to relieve acute inflammation of mucous membranes with swelling and stinging, burning pain improved by cold applications. If these symptoms are present, Apis might be indicated. However, Apis is not used to drain cysts or reduce them. Meanwhile, Colocynthis 6C can be used for dull pain causing nausea. We recommend you consult with a health care professional about specific treatment options for your condition.

Gunjan Bhatnagarsays:

I have a sudden Urtecaria outbreak from 5 days after 3 years and it is slowly increasing the spread over the hands and legs. I have a chronic Urtecaria from past 25 years. I took Urtica Urens for 1 year and had no outbreak in the last 3 years. Can I take Apis Mellifica 30 to get rid of hives or should I also take Urtica Urens 6C and Histaminium 30C?
Please suggest the dosage as well.


Hello Gunjan, we recommend you use the Boiron Medicine Finder app ( to search for your symptoms and medicine options. We do have a protocol for hives in the First Aid section, which includes how to use Apis mellifica 30C, Histaminum 30C, and Urtica Urens 6C. If you are experiencing ongoing outbreaks of urticaria, we do urge you to visit a medical professional. Hope you feel better soon!

Gunjan Bhatnagarsays:

Thank you for your reply Boiron. I am not able to download this app due to some download restrictions. Is there any website where I can search the medicines with symptoms and know the dosage?

If not, can you please help me with the dosage for these medicines?

For the time being, I am taking allopathic anti histamine tablet and have some relief.


Hi Gunjan, you can access the Medicine Finder on any browser, no download required! Here’s the link:

Jeff Brownsays:
I was told I should try apis mellifica for a strained voice. I talk a lot and sing and need something for a stressed voice. Thank you Jeff


Hi Jeff, hope you give Apis a try and keep us updated! There are other homeopathic options for a stress or strained voice, including Arum triphyllum 6C for loss of voice with a scratchy throat, Causticum 6C for strained vocal cords, and Rhux tox 6C for overexerted vocal cords. Boiron also offers a multi-symptom medicine called ThroatCalm that contains a number of homeopathic active ingredients to relieve hoarseness and minor sore throat.


Hi I was diaganose by a dermatologist that I have celiac disease. I have been taking depsone for the last 30 days and some 5mg steroids, it helped a little bit but not cure. I am on a gluten free diet as well.
In homeopathy treatment which medicine can help me. Apis Mellifica, Natrum Mur., or Aurum Metallicum.
It would be great help if you can guide me.


Hi Kookie, homeopathic treatments for chronic conditions are very specific to each patient. There may be a homeopathic treatment that addresses your condition, but we recommend consulting a practitioner knowledgeable in homeopathy. If you do not have a practitioner, please contact the National Center for Homeopathy at 856-437-4752 or visit






Hello Krishna, sorry to hear about your feet. As manufacturer, we cannot offer suggestions for your specific condition. We recommend you consult a health care practitioner knowledgeable in homeopathy. If you do not have a practitioner, please contact the National Center for Homeopathy at 856-437-4752 or visit


I wonder if apis mellifica would help with severe food allergic reactions such as peanuts, milk, sesames, soy etc


Hello Arlene, Urtica urens is indicated for skin rashes from food allergies; however, our medicines are intended to relieve self-treatable, everyday conditions. Severe food allergies can be life threatening, so we recommend you seek the help of a medical professional.

Jaspal singhsays:

I want to Color my hair n my beard but i used its patch before to apply n i got itching swallowed skin with water now 8 days get passed still its not fully cure Some one suggest me for Apis 200 Can i use it for this problem or tell me what should i do


Hi Jaspal, sorry to hear about your skin reaction. Yes, Apis mellifica 30C can help relieve pink, swollen skin with itching that is improved by cold compresses. However, there are a few other homeopathic medicines for skin issues that might help. We recommend you use the free Boiron Medicine Finder app to help select which one is right for you. Just go into into the “First Aid – Skin” section and look from there. If your condition lasts for more than 3 days or worsens, we recommend you speak to a physician.


I have problem with right eye mild to severe twitches and feels swollen and full just above inner canthus in corner
Started 3 years ago after sinus infection. Worse with light. I have an ointment which contain apis
Would this be the right medicine to use. Thank You


Hello Jay, Apis may help, but first you should read the label on the ointment to find out if it’s suitable for use around your eyes. Be careful when applying to avoid getting any in your eye. For a more convenient treatment, we recommend using Apis orally in pellet form. Simply place the pellets in your mouth and melt under your tongue. Here’s the link to Apis pellets in our shop:


What is the difference between Apis 30c and Apis 30ch? Thank you!


Hello Kristen, great question. There is no difference between Apis 30C and Apis 30CH. Both “C” and “CH” stand for Centesimal Hahnemannian scale, which is a scale of dilution where each dilution is a 1/100 dilution of the previous one. “CH” is just an alternative abbreviation used outside of the U.S. Hope that helps!

Josie Chavezsays:

I recently was told that I could put apis mellifica in water and then directly put on bug bites. How many pellets and how much water would you recommend? When bugs bite my son, his skin swells and the affected area is quite itchy.


Hello Josie, your question had me stumped! I consulted with our resident pharmacist and he says that the medicine is not easily absorbed by the skin when diluted with water, plus it would dry too fast before the medicine could really soak in. He recommends using Apis pellets orally as they are quickly absorbed in the mouth and will provide the best results.

If you want something soothing for your son’s skin, you may want to try Calendula Gel. It’s great for bug bites and has a refreshing, cool feeling. It’s safe to use this alongside Apis pellets, too. Here’s the link in our shop:


Hello, I am confused.. is Apis Mellifica made from dead crushed honeybees?


Hi Lydia, yes, Apis mellifica is made from a tincture of honeybees in accordance with the United States Homeopathic Pharmacopoeia and FDA regulations. Homeopathic medicines have active ingredients that originate from animals, plants, or minerals.

Kumar Sunilkumar Pawarsays:

So, if a malaria mosquito bites then we should crush another malaria mosquito, dilute it and eat it?


Hello Kumar, unfortunately it is not that simple. Homeopathic medicines are obtained from a precise and controlled process of successive homeopathic dilutions, from specific substances provided in the homeopathic pharmacocpoeia. With each dilution, the medicine is deconcentrated and then vigorously shaken (also called “succussion”) with specialized equipment. This process transforms the original solution into a therapeutically active medicine. We do not recommend making your own.

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