A Simple Alternative to Antihistamines


Does your favorite rose bush leave you sneezing, or a bug bite cause an itchy welt on your arm? Chances are you’ve popped a little pink antihistamine pill looking for help. Antihistamines block the body’s histamine receptors. Histamine is a substance released by cells when something harmful is detected like an allergen such as a flower’s pollen or the sting of an insect. These drugs provide some relief, but your symptoms will come roaring back once they’ve worn off. They also come with that one big drawback you know all too well — excessive sleepiness — because they inhibit other essential functions that histamine has in your body.

Fortunately, homeopathy has a simple answer for those suffering from allergies. Histaminum hydrochloricum is a versatile remedy that works for a range of allergic conditions.

How Histamine Works

Histamine is present in the cells and tissues throughout your body, and it’s also naturally occurring in the venom of wasps, bees, and jellyfish. People with allergies may view histamine as the enemy, but it serves a necessary purpose.

On a basic level, histamine helps protect the body and get rid of things that bother you. For instance, histamine gets released during injuries and infections. It works to increase blood flow in the affected area for the benefit of healing. It’s this blood flow effect (vasodilation) that unfortunately causes you to itch, sneeze, or tear up in response to an allergen, which your body perceives as a threat and attacks. As a neurotransmitter, histamine also sends signals to your stomach to produce acid and to your brain to keep you alert, which is the reason antihistamines can leave you feeling sluggish.

Issues arise when histamine levels are excessive, as is the case with allergic conditions. In these situations, harmless substances like food or pollen can set off rapid production of more histamine. As you continue to encounter these triggers, histamine production stays high and leads to those well-known and annoying reactions in our eyes, nose, and skin.

Histaminum Hydrochloricum for Allergies

Histaminum hydrochloricum is prepared from a salt of histamine called histamine dihydrochloride. Unlike antihistamines that block the body’s response, a microdose of histamine dihydrochloride can help your body regulate how much histamine it naturally makes. Therefore, you’ll get all the benefits of allergy relief without feeling drowsy.

This “blue tube” medicine is so versatile that you’ll want to keep it always stocked in your first aid kit. It relieves symptoms of allergic conditions, including hay fever.* You can find it as an active ingredient in RhinAllergy for this purpose. It’s also a useful remedy for hives and reactions to insect stings.*

For general use throughout allergy season and beyond, dissolve 5 pellets of Histaminum hydrochloricum 30C under the tongue three times a day until symptoms are relieved. When treating hives and other skin reactions, use 5 pellets every hour, then decrease the frequency as your symptoms improve.

Want to learn more about the homeopathic uses of Boiron Histaminum hydrochloricum? Watch this video featuring pharmacist Gary Kracoff, NMD, R.Ph.

*Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.

Just for our blog readers! Get 10% off this medicine with coupon code BLOG when you enter at checkout.

Comments (19)

Linda Brownsays:

Hello, My husband is in ICU right now but not on a ventilator,, but on high flow oxygen.. The Dr. is saying he doesn’t have a lot of mucous but has inflammation.. Would Histamine 30 CH help him in any way..


Hello Linda, so very sorry about your husband and we wish him a speedy recovery. Homeopathic treatments for chronic conditions are very specific to each patient. There may be a homeopathic treatment that addresses your condition, but we recommend consulting a practitioner knowledgeable in homeopathy. You can contact the National Center for Homeopathy at (856) 437-4752 or visit to find one in your area.

Annie Oceansays:

I am having a rash spreading over my body from exposure to two covid vaccinated people..
what homeopathy could I use for this?


Thanks for your question, Annie. At this point, not much is known about the effect of the COVID-19 vaccine on homeopathic medications and vice versa. For information about specific drugs, check with your health care provider.

Maria fiskesays:

I have narrow angle glaucoma , and I want to know if this is safe to take it …. I have always take them and I love them …… I know I can’t take over the counter ,regular Medicine for allergies …. This is my only hope


Hello Maria, yes it is safe to take. Histaminum doesn’t contain decongestants or conventional antihistamines, which, in allopathic medications, are responsible for the interference with glaucoma. Additionally, Histaminum has no known interactions with other medications.


I’m allergic to antihistamines. It causes me to itch but mostly I cough. Would this help?


Sorry. I forgot to say would this medicine help for those who are allergic to antihistamine.


Hello Cheryl, yes, Histaminum works with your body to relieve allergy symptoms brought on by the overproduction of histamine. It doesn’t mask or suppress, so it makes a great alternative to conventional antihistamines that only work by blocking histamine.

Emily Hsays:

Hello! I am looking for a homeopathic option for an antihistamine that will clear up postnasal drip/congestion. I am currently breast-feeding. I purchased Histaminum Hydrochloricum – is this the correct one for what I am trying to accomplish? And is this breast-feeding safe? Thanks so much!


Hi Emily, Histaminum is a great first choice for allergy relief and there is also Hydrastis canadensis if postnasal drip is your main symptom. You can take both together during an allergy flare-up if needed; however please ask your health care professional before taking any medicine, including Boiron homeopathic medicines. If your health care professional needs more information on our medicines, they can contact us at 1-800-BOIRON-1.

Rakesh Dadlanisays:

I started taking boiron histamine hydrochlorium 30 c three pellets under the tongue for nasal allergy it has a lot of side effects like cold sweat, drowsiness, excessive sleep all daywith n throat dry mouth and gets your body temperature down even if you don’t have fever. But the medicine says a different story that it has no side effects. So I stopped it immediately.


Hi Rakesh, can you please give us a call at 1-800-BOIRON-1 so we can learn more about what happened? Thank you.


Hi which homeo medicine is good for GERD , regurgitation. Thank You


Hi Sneha, GERD is a digestive disorder that requires diagnosis by a professional. But for occasional bouts of heartburn and acid indigestion, check out Boiron Acidil.


Our older teenager has allergies and a hand eczema breakout including blisters and red spots. Is it safe to take Histaminum hydrochloricum 30c and Sulfur 200ck together?


Thank you for your question, David. Yes, it is safe to take more than one homeopathic medicine at the same time. They can be taken together and there’s no need to stagger or alternate the doses.


I was recently stung by a yellow jacket wasp, and a few days later have a about a 2 inch rash that itches. Is Histaminum Hydrochloricum what I need to take? And is it safe to take during pregnancy?


Hi Keri, Histaminum relieves symptoms of allergies, including reactions from insect stings. You can try that on its own or take it alongside Urtica urens if needed for additional relief from skin rashes with itching due to allergies. If you are pregnant or breastfeeding, we recommend you speak to your health care professional before taking any medication, including Boiron medicines. Thank you!

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