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Research & Studies

Homeopathy Research Update

Currently, there are more than 5,000 studies on homeopathy available to health care professionals on Pubmed, the leading search engine for scientific research. Clinical research is providing  evidence of the efficacy of homeopathic medicines, and basic laboratory research is confirming the biological activity of highly diluted substances and helping the scientific community better understand their mechanism of action.

Physical Research

Thermoluminescence of ultra-high dilutions of lithium chloride and sodium chloride. Rey L. Physica A 323 (2003) 67-74

Ultra-high dilutions of LiCl and NaCl (10-30 g. cm-3) have been irradiated by X and g-rays at 77 K, then progressively rewarmed to room temperature. During that phase, their thermoluminescence has been studied and it was found that, despite their dilution beyond the Avogadro number, the emitted light was specific of the original salts dissolved initially.

Demangeat JL. Nanosized solvent superstructures in ultramolecular aqueous dilutions: twenty years’ research using water proton NMR relaxation. Homeopathy. 2013 Apr;102(2):87-105. doi: 10.1016/j.homp.2013.01.001

Biological Research

Doutremepuich C et al Paradoxical effects of Aspirin.. Thrombosis 2012; 2012:676237

In the absence of COX 1, ultra-low doses of aspirin produce an antihemorrhagic effect not observed with intermediate doses. The absence of COX 2 induced a hemorrhagic effect that needs further research, probably originated in compensatory phenomena.

Bellavite P et al. Assays of homeopathic remedies in rodent behavioural and psychopathological models. Homp 2009; 98, 208–227

Magnani P et al Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice Psychopharmacology DOI 10.1007/s00213-010-1855-2

Venard C et al. Comparative Analysis of Gelsemine and Gelsemium sempervirens activity on Neurosteroid Allopregnanolone Formation in the Spinal Cord and Limbic System. eCAM 2009 doi:10.1093/ecam/nep083

Mohammadi R et al. Homeopathic treatment for peripheral nerve regeneration: an experimental study in a rat sciatic nerve transection model. Homeopathy 2012; 101: 141-146.

Kokornaczyk M et al. Polycrystalline structures formed in evaporating droplets as a parameter to test the action of Zincum metallicum 30c in a wheat seed model. Homeopathy (2016) 105, 173-179

Olioso D. et al.: Arnica montana effects on gene expression in a human macrophage cell line. Evaluation by quantitative Real-Time PCR. Homeopathy. 2016 May;105(2):131-47. doi: 10.1016/j.homp.2016.02.001.

Puhlmann J et al.: Immunologically active polysaccharides of Arnica montana cell cultures. Phytochemistry. 1991;30(4):1141-5.

Lynn G. et al.: Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB. Biol Chem. 1997 Sep;378(9):951-61.

Clinical Research

Frass M. et al. Influence of potassium dichromate on tracheal secretions in critically ill patients. Chest 2005 Mar, 127(3): 936-41

The study suggest that diluted and vigorously shaken potassium dichromate may help to decrease the amount of stringy tracheal secretions in COPD patients.

Taylor MA et al. Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series. BMJ 2000; 321:471-6

Bell I et al. Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo Rheumatology 2004;43:577–582

Papp R. et al. Oscillococcinum® in patients with influenza-like syndromes: A placebo-controlled double-blind evaluation. British Homeopathic Journal 1998, 87, 69-76

Berrebi A. Treatment of pain due to unwanted lactation with a homeopathic preparation given in the immediate post-partum period. Journal of Gynecology, Obstetrics and Biological Reproduction 30; 353-357

Mathie RT. Controlled clinical studies of homeopathy. Homeopathy 2015;104:328-332

Mathie RT et al. Randomized placebo-controlled trials of individualized homeopathic treatment: systematic review and meta-analysis. Syst Rev 2014;3:142

5th International CEDH Conference – June 24-26, 2016

A recent meta-analysis of clinical studies on homeopathic medicines.


Dossett M et al. Homeopathy Use by US Adults: Results of a National Survey. AJPH 2016 doi: 10.2105/AJPH.2015.303025

Witt C et al Outcome and costs of homoeopathic and conventional treatment strategies: A comparative cohort study in patients with chronic disorders. Complementary Therapies in Medicine (2005) 13:79-86 doi:10.1016/j.ctim.2005.03.005

Riley D, Fischer M, Singh B, et al. (2001). Homeopathy and Conventional Medicine: An Outcomes Study Comparing Effectiveness in a Primary Care Setting. Journal of Alternative and Complementary Medicine, 7:149–159.

Haidvogl M Riley D, Heger M et al. Homeopathic and conventional treatment for acute respiratory and ear complaints: A comparative study on outcome in the primary care setting. BMC Complement Altern Med. 2007; 7: 7. doi: 10.1186/1472-6882-7-7

Grimaldi-BensoudaL, Begaud B, Lert F, et al. Benchmarking the burden of 100 diseases: results of a nationwide representative survey within general practices. BMJ Open 2011;1: e000215. doi:10.1136/bmjopen-2011- 000215

Rossignol M. et al.: Benchmarking clinical management of spinal and non-spinal disorders using quality of life: results from the EPI3-LASER survey in primary care. Eur Spine J (2011) 20:2210–2216 DOI 10.1007/s00586-011-1780-z

Rossignol M. et al. Who seeks primary care for musculoskeletal disorders (MSDs) with physicians prescribing homeopathic and other complementary medicine? Results from the EPI3-LASER survey in France. BMC Musculoskeletal Disorders 2011, 12:21 http://www.biomedcentral.com/1471-2474/12/21

Grimaldi-Bensouda L, Engel P,Massol J, et al. Who seeks primary care for sleep, anxiety and depressive disorders from physicians prescribing homeopathic and other complementary medicine? Results from the EPI3 population survey. BMJ Open 2012; 2:e001498. doi:10.1136/bmjopen-2012-001498

Rossignol M. et al.: Impact of physician preferences for homeopathic or conventional medicines on patients with musculoskeletal disorders: results from the EPI3-MSD cohort. Pharmacoepidemiology and Drug Safety Volume 21, Issue 10, pages 1093–1101, October 2012. DOI: 10.1002/pds.3316

Lert F. et al.: Characteristics of patients consulting their regular primary care physician according to their prescribing preferences for homeopathy and complementary medicine. Homeopathy. January 2014 , 103, 51–57

Grimaldi-Bensouda L, Bégaud B, Rossignol M et al. Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008. PLoS One. 2014 19;e89990. doi: 10.1371/journal.pone.0089990 


Homeopathy and Pharmaceutical care. Boiron M. and Roux F. Edition Similia

Written by pharmacists for pharmacists. 53 protocols addressing the most frequent conditions seen at the counter.

Pharmacology and Homeopathic Materia medica. CEDH.

A modern and updated references, with 326 homeopathic medicines, their pharmacology and indications, including regimens.

Gudrun Bornhöft, Peter F. Matthiessen (eds). Homeopathy in Healthcare – Effectiveness, Appropriateness, Safety, Costs: An HTA report on homeopathy as part of the Swiss Complementary Medicine Evaluation Program. Springer 2011

A complete evaluation of the interest of homeopathy in healthcare, prepared for the Swiss Government to evaluate its integration into State Healthcare Program.